Challenges for the macro-scale of the global economy

After reading Institutional macro-structures of the global economy p.54 I believe the challenges that global companies face is the ever evolving treaties and regulations that are made between Countries, These treaties are somewhat liquid in where commerce can flow from one nation to another while being blocked from entering a third nation.

The global economy on a macro scale as measured with the GDP of a country could be indicators of challenges one could face, other indicators are Unemployment, income, and inflation as it relates to the country, and on the macro scale as compared to the globe. While globalization has allowed us to transfer goods/services around the world the challenges have increased due to all the pacts and treaties signed between Countries and organizations.